Chris Holland

Chris Holland

Presently: PhD student supervised by Dr Andrew Godkin and Dr David Cole at Cardiff University, School of Medicine and based within the Henry Wellcome Research Institute. My PhD project, co-funded by the medical research council (MRC) and the Infection, Immunity and Inflammation Interdisciplinary Research Group (I3-IRG) focuses on understanding CD4+ TCR recognition of the peptide-major histocompatibility complex class II (pMHC-II) molecule, a fundamental event of adaptive immunity, and how this interaction can be enhanced to improve diagnostic tools and develop novel vaccine strategies.

2008-2009: Team supervisor within the hospital services department of the NHS Blood and Transplant facility in Bristol, UK.

2005-2008: Attended the University of the West of England in Bristol where I achieved a higher second class honours Bsc in Applied Biological sciences. In my final year I undertook a research project looking at Nociceptin; a molecule commonly associated with pain perception and the central nervous system. However, my project focused upon its role in a novel bi-directional communication pathway between the nervous and immune systems, specifically investigating its affects upon T cell modulation.