Dr John Bridgeman - Publications

Journal Publications

8) Cheadle EJ, Rothwell DG, Bridgeman JS, Sheard VE, Hawkins RE, Gilham DE.Ligation of the CD2 co-stimulatory receptor enhances IL-2production from first generation Chimeric Antigen Receptor T cells.Gene Therapy, 2011, Dec 1.

7) Bridgeman JS, Sewell AK, Miles JJ, Price DA, Cole DK.Structural and biophysical determinants of αβ T-cell antigen recognitionImmunology, 2011, Oct 4.

6) Holland M, Castro FV, Alexander S, Smith D, Liu J, Walker M, Bitton D, Mulryan K, Ashton G, Blaylock M, Bagley S, Connolly Y, Bridgeman J, Miller C, Krishnan S, Dempsey C, Masurekar A, Stern P, Whetton A, Saha V.RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia.Blood. 2011 Jul 21;118(3):638-49.

5) Rothwell DG, Crossley R, Bridgeman JS, Sheard V, Zhang Y, Sharp T, Hawkins RE, Gilham D, McKay TR. Functional expression of secreted proteins from a bicistronic retroviral cassette based on foot-and-mouth disease virus 2A can be position-dependent. Hum Gene Ther. 2010 Nov;21(11):1631-7.

4) Bridgeman JS, Hawkins RE, Bagley S, Blaylock M, Holland M, Gilham DE. The optimal antigen response of chimeric antigen receptors harboring the CD3zeta transmembrane domain is dependent upon incorporation of the receptor into the endogenous TCR/CD3 complex. J Immunol. 2010 Jun 15;184(12):6938-49.

3) Bridgeman JS, Hawkins RE, Hombach AA, Abken H, Gilham DE. Building better chimeric antigen receptors for adoptive T cell therapy. Curr Gene Ther. 2010 Apr;10(2):77-90.

2) Bridgeman JS, Blaylock M, Hawkins RE, Gilham DE. Development of a flow cytometric co-immunoprecipitation technique for the study of multiple protein-protein interactions and its application to T-cell receptor analysis. Cytometry A. 2010 Apr;77(4):338-46.

1) Bridgeman JS, Gilham DE, Hawkins RE, Cheadle EJ. The second cellular therapy of cancer symposium, 27-29 March 2009, Milan, Italy. Cancer Immunol Immunother. 2010 Jun;59(6):971-4.