Useful links

UK Immunology

British Society for Immunology

South Wales Immunology

Cardiff University Immunology Research Groups

Cardiff University Infection, Immunity and Imflamation Research

Immunology in Cardiff

Life in South Wales

T-cell resources

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Wikipedia

T-cells

CD8

Cytotoxic T-cells

T-cell receptor

Memory T-cells

Regulatory T cells

Structural Movies

Movies open in new window in .wmv format.

1. A24VYG rotation (A24 in blue and yellow. Peptide coloured by thermal parameter. Molecule spins 180 degrees).

2. DR1HA rotation +gly (DR1HA in green and cyan. Peptide coloured by thermal parameter. N-linked glycosylation sites shown in yellow sticks. Molecule spins 180 degrees).

3. HA17TCR rotation +gly (HA17TCR in green and blue. N-linked glycosylation sites shown in yellow sticks. Molecule spins 180 degrees).

4. MHC TCR CD8 docking rotation (MHC in blue and yellow. Peptide coloured by thermal parameter. TCR in green and yellow. CD8 in red and purple. Peptide, TCR and CD8 dock. Molecule spins 180 degrees).

5. A24VYGpep dock binding groove (A24 in blue and yellow. Peptide coloured by thermal parameter. Peptide docks, then the view zooms in and stops at the binding groove).

6. A24VYGpep dock tour (A24 in blue and yellow. Peptide coloured by thermal parameter. Peptide docks, then the view zooms in and stops at the binding groove, then zooms into the CD8 binding loop).

7. Human triple class I (MHC in dark green and mauve. Peptide coloured by thermal parameter. TCR in green and yellow. CD8 in red and purple. N-linked glycosylation sites shown in yellow sticks. Molecule spins 180 degrees).

8. Human triple class II (MHC in green and cyan. Peptide coloured by thermal parameter. TCR in orange and blue. CD4 in red. N-linked glycosylation sites shown in yellow sticks. Molecule spins 180 degrees).

9. Murine triple class I (MHC in dark green and mauve. Peptide coloured by thermal parameter. TCR in green and yellow. CD8 in red and purple. N-linked glycosylation sites shown in yellow sticks. Molecule spins 180 degrees).

10. Murine triple class II (MHC in dark green and mauve. Peptide coloured by thermal parameter. TCR in green and yellow. CD4 in red. N-linked glycosylation sites shown in yellow sticks. Molecule spins 180 degrees).

Scientific tools

http://www.ncbi.nlm.nih.gov/sites/entrez (Pubmed)

http://www.biocompare.com/ (Science products comparison site)

http://www.expasy.ch/ (Expasy Proteomics resources)

http://imgt.cines.fr/ (MHC database)

http://apps.isiknowledge.com/ (ISI web of knowledge)

http://www.rcsb.org/pdb/home/home.do (Protein data base)

http://pymol.sourceforge.net/ (Pymol structural viewer)

http://www.ysbl.york.ac.uk/~emsley/coot/ (Structural tools)

http://www.ccp4.ac.uk/main.html (X-ray crystallography tools)